Quick reference
Guidelines
What the major guidelines recommend on 41 common topics, grouped by specialty, each linked to its source. The list is checked every morning for new and updated guidelines.
41 topics in 10 specialties
New and updated guidelines
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EASL-EASD-EASO Guidance for the Use of Resmetirom and Semaglutide as MASH-Targeted Therapy
The joint EASL-EASD-EASO guidance recommends resmetirom or semaglutide for adults with non-cirrhotic MASH and fibrosis stages 2-3, alongside lifestyle intervention and optimized comorbidity management. It addresses treatment selection, initiation, monitoring, and discontinuation, and advises against using these agents as MASH-targeted therapy in adults with MASH cirrhosis until further data are available.
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AGA Clinical Practice Update on Surveillance of Pancreatic Cystic Lesions and Hepatocellular…
The AGA advises individualized decisions about pancreatic cyst and hepatocellular carcinoma surveillance in older adults, considering comorbidities, life expectancy, risks, and treatment candidacy. It recommends considering when to stop surveillance through shared decision-making.
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2026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management…
The ACC/AHA guideline recommends approaches to perioperative cardiovascular evaluation and management for adults undergoing noncardiac surgery, including pharmacological therapies, monitoring, and devices for cardiovascular disease and associated conditions.
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Clinical Practice Guideline for the Diagnosis and Treatment of Urinary Tract Infection in Children…
The AAP guideline provides recommendations for diagnosing and managing urinary tract infections in children 8 days to 5 years of age with low medical complexity. It covers medical evaluation, antibiotic treatment, imaging, prevention strategies, and evaluation and treatment of bowel and bladder dysfunction.
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2026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management…
The ACC/AHA guideline recommends approaches to perioperative cardiovascular evaluation and management for adults undergoing noncardiac surgery, including evidence-based strategies for cardiovascular disease and associated conditions.
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Tobacco Use Treatment: Synopsis of the 2026 U.S. Department of Veterans Affairs and U.S. Department…
The 2026 VA/DoD guideline recommends motivational interviewing and FDA-approved pharmacotherapies to increase abstinence from combustible tobacco, with varenicline preferred over other single-agent medications and combination NRT preferred over NRT alone. It also addresses treatment for smokeless tobacco, electronic nicotine delivery systems, and patients not ready to quit within 30 days.
Cardiology
- Hypertension: diagnosis & targetConfirm elevated office blood pressure with home or ambulatory monitoring before diagnosis, and generally target below 130/80.ACC/AHA 2025 · USPSTF 2021 · AAFP 2022
- Statins for primary preventionUse PREVENT to estimate risk and discuss statins with adults at borderline or intermediate risk.USPSTF 2022 · ACC/AHA 2026 · VA/DoD 2025
- Aspirin for primary prevention of cardiovascular diseaseIndividualize aspirin for adults 40 to 59 with 10% or greater CVD risk and no increased bleeding risk.USPSTF 2022 · ACC/AHA 2019 · ADA 2026
- Atrial fibrillation: stroke prevention and anticoagulationAnticoagulate at annual thromboembolic risk ≥2%/yr; prefer DOACs unless mechanical valve or moderate to severe rheumatic mitral stenosis.ACC/AHA/ACCP/HRS 2023 · USPSTF 2022
- Heart failure with reduced ejection fraction (GDMT)For HFrEF with LVEF ≤40%, start all four pillars and titrate to target or maximally tolerated doses.ACC/AHA/HFSA 2022
- Abdominal aortic aneurysm screeningOffer one time ultrasound screening to men aged 65 to 75 who have ever smoked.USPSTF 2019 · ACC/AHA 2022
- ECG screening (asymptomatic adults)Avoid resting or exercise ECG screening to prevent cardiovascular events in asymptomatic, low risk adults.USPSTF 2022 · ACC/AHA 2025 · Choosing Wisely / AAFP 2012
- Preoperative cardiac risk for noncardiac surgeryPostpone elective surgery for active cardiac conditions; otherwise estimate risk and test only if results would change management.ACC/AHA 2024 · ASA, AGA, ASMBS, ISPCOP and SAGES 2024
New in Cardiology
Endocrinology
- Type 2 diabetes: screening & A1c targetScreen all adults ≥35 for diabetes and individualize A1C goals, with <7% appropriate for most nonpregnant adults.USPSTF 2021 · ADA 2026
- Type 2 diabetes: drug selectionChoose therapy by comorbidities and goals first; use agents with proven cardiovascular or kidney benefit when indicated.ADA 2026 · ACP 2024
- Hypothyroidism managementLevothyroxine is first line; titrate to reference range TSH and recheck 4 to 6 weeks after dose changes.ATA 2026 · USPSTF 2015 · BMJ Rapid Recommendations 2019
- Obesity & weight managementOffer intensive behavioral intervention to adults with BMI ≥30, and pair eligible obesity medication with lifestyle therapy.USPSTF 2018 · AACE 2025 · ASMBS/IFSO 2022 · ACC 2025
- Osteoporosis screeningScreen women 65 or older and younger postmenopausal women at increased risk; BHOF recommends testing men 70+.USPSTF 2025 · BHOF 2022
- Osteoporosis treatmentTreat high fracture risk with bisphosphonates first line, and never stop denosumab without transitioning to another antiresorptive.AACE 2020 · ACP 2023 · Endocrine Society 2020
- Gestational diabetes screeningScreen for gestational diabetes at 24 to 28 weeks in pregnant persons not already diagnosed.USPSTF 2021 · ACOG 2024 · ADA 2026
New in Endocrinology
Oncology (cancer screening)
- Breast cancer screeningOffer biennial mammography to women 40 to 74 (USPSTF); ACP advises a shared decision at 40 to 49.USPSTF 2024 · ACS 2015 · ACOG 2024 · ACP 2026
- Cervical cancer screeningScreen from 21 (USPSTF) or 25 (ACS); primary HPV testing every 5 years is preferred through 65.USPSTF 2018 · ACS 2025 · ASCCP (multisociety consensus) 2020 · ASCCP (enduring guidelines) 2025
- Colorectal cancer screeningFor average-risk adults, begin screening at 45, continue through 75, and individualize decisions from 76 to 85.USPSTF 2021 · ACS 2026 · Multi-Society Task Force (ACG/AGA/ASGE) 2022 · ACP 2023
- Lung cancer screeningOffer annual low-dose CT to asymptomatic adults 50 to 80 with a ≥20 pack-year history who currently or formerly smoked.USPSTF 2021 · ACS 2023 · CHEST (ACCP) 2021
- Prostate cancer screening (PSA)Offer men 55 to 69 a shared decision about PSA screening; do not screen at 70 or older (USPSTF).USPSTF 2018 · AUA / SUO 2026 · ACS 2010
Infectious disease
- Community-acquired pneumonia (outpatient): empiric antibiotic therapyFor CAP, use amoxicillin, doxycycline, or an eligible macrolide without comorbidities; with comorbidities, use combination therapy or fluoroquinolone.ATS/IDSA 2019 · ATS 2025
- Acute rhinosinusitis / URI antibioticsMost acute rhinosinusitis is viral; use watchful waiting for uncomplicated bacterial sinusitis when follow up is assured.AAO-HNSF 2025 · CDC 2024
- Group A strep pharyngitisUse clinical scoring to identify low risk patients who usually do not need testing.IDSA 2025 · CDC 2025
- Uncomplicated UTI (cystitis) in womenFor acute uncomplicated cystitis, use nitrofurantoin 100 mg twice daily for 5 days as a first line treatment.IDSA 2025 · AUA/CUA/SUFU 2025 · USPSTF 2019
- HIV screeningScreen patients aged 13 to 64 at least once; rescreen annually if ongoing HIV risk.USPSTF 2023 · CDC 2025
- Hepatitis C screeningScreen all adults at least once and during each pregnancy, confirming positive antibody tests with HCV RNA.USPSTF 2020 · CDC 2020 · AASLD/IDSA 2023
- Latent tuberculosis infection (LTBI) screeningScreen asymptomatic adults 18 and older at increased risk for latent tuberculosis infection using a TST or IGRA.USPSTF 2023 · ATS/IDSA/CDC 2017 · CDC/NTCA 2020
- Chlamydia & gonorrhea screeningScreen sexually active women under 25 annually for chlamydia and gonorrhea, and those 25 and older if at increased risk.USPSTF 2021 · CDC 2024
- Adult immunizationsAdults should receive annual influenza and updated COVID vaccines, with other vaccines guided by age, pregnancy, and risk.CDC / ACIP 2025 · AAFP 2026 · ACP 2026
Pulmonology
- Asthma management (stepwise)For adults and adolescents, prefer as-needed low-dose ICS-formoterol at every step, with maintenance MART at Steps 3 to 4.NAEPP / NHLBI 2020 · GINA 2026
- COPD management: GOLD ABE assessment and initial inhaler therapyUse a long-acting bronchodilator for Group A and LABA plus LAMA for Groups B and E.GOLD 2026 · USPSTF 2022 · ATS 2023
- Lung cancer screeningOffer annual low-dose CT to asymptomatic adults 50 to 80 with a ≥20 pack-year history who currently or formerly smoked.USPSTF 2021 · ACS 2023 · CHEST (ACCP) 2021
- Tobacco use screening and cessationAsk all adults about tobacco use, advise quitting, and offer counseling plus approved cessation medication to nonpregnant adults.USPSTF 2021 · ATS 2020 · VA/DoD 2026
Rheumatology and pain
- Gout managementAllopurinol is preferred first line urate lowering therapy, titrated to a serum urate goal of <6 mg/dL.ACR 2020
- Acute low back painUse nondrug therapy first for uncomplicated acute low back pain; avoid imaging absent red flags.ACP 2017 · ACR (Appropriateness Criteria) 2021 · CDC 2022
- Opioid prescribing for chronic painFor chronic pain, maximize nonopioid care, avoid initiating opioids, and do not abruptly stop established opioid therapy.CDC 2022 · VA/DoD 2022
- Osteoporosis treatmentTreat high fracture risk with bisphosphonates first line, and never stop denosumab without transitioning to another antiresorptive.AACE 2020 · ACP 2023 · Endocrine Society 2020
OB/GYN
- Menopause and hormone therapyFor bothersome menopausal symptoms, individualize hormone therapy by age and timing; add progestogen if the uterus is present.The Menopause Society 2023 · USPSTF 2022
- Gestational diabetes screeningScreen for gestational diabetes at 24 to 28 weeks in pregnant persons not already diagnosed.USPSTF 2021 · ACOG 2024 · ADA 2026
- Cervical cancer screeningScreen from 21 (USPSTF) or 25 (ACS); primary HPV testing every 5 years is preferred through 65.USPSTF 2018 · ACS 2025 · ASCCP (multisociety consensus) 2020 · ASCCP (enduring guidelines) 2025
- Breast cancer screeningOffer biennial mammography to women 40 to 74 (USPSTF); ACP advises a shared decision at 40 to 49.USPSTF 2024 · ACS 2015 · ACOG 2024 · ACP 2026
Psychiatry and addiction
- Depression & anxiety screeningScreen all adults for depression and adults under 65 for anxiety.USPSTF 2023 · ACP 2023
- Unhealthy alcohol use screening and counselingScreen all adults for unhealthy alcohol use and counsel those with risky or hazardous drinking.USPSTF 2018 · APA 2018
- Tobacco use screening and cessationAsk all adults about tobacco use, advise quitting, and offer counseling plus approved cessation medication to nonpregnant adults.USPSTF 2021 · ATS 2020 · VA/DoD 2026
- Opioid prescribing for chronic painFor chronic pain, maximize nonopioid care, avoid initiating opioids, and do not abruptly stop established opioid therapy.CDC 2022 · VA/DoD 2022
New in Psychiatry and addiction
Geriatrics
- Falls prevention in community-dwelling older adultsFor community-dwelling adults 65 and older at increased fall risk, recommend exercise interventions targeting gait, balance, function, or resistance.USPSTF 2024 · World Falls Guidelines 2022
- Beers Criteria: potentially inappropriate medications in older adultsUse the 2023 AGS Beers Criteria to support shared decision making and deprescribing, not as a punitive rule.AGS 2023
- Osteoporosis screeningScreen women 65 or older and younger postmenopausal women at increased risk; BHOF recommends testing men 70+.USPSTF 2025 · BHOF 2022
Nephrology
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These summaries are for general reference only. They are not official guidance and not medical advice. Guidelines are updated often, so check the issuing organization’s own website for the current version before relying on any recommendation.