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Latent tuberculosis infection (LTBI) screening

What the major U.S. guidelines recommend, with a link to verify each at the source. A quick-reference summary for clinicians, not medical advice.

USPSTF · 2023 · Grade B

Screen asymptomatic adults 18 and older at increased risk: persons born in or who lived in countries with high TB prevalence, and persons who live in or have lived in high-risk congregate settings (homeless shelters, correctional facilities). Test with TST or IGRA. No evidence on optimal screening interval; a reasonable approach ranges from one-time screening for those at low risk of future exposure to annual screening for those with continued exposure. Does not apply to symptomatic adults or to children.

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