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Adult immunizations

What the major U.S. guidelines recommend, with a link to verify each at the source. A quick-reference summary for clinicians, not medical advice.

CDC / ACIP · 2025

Influenza annually (all ≥6mo). Tdap once then Td/Tdap q10y. Zoster (RZV) 2 doses ≥50 (and ≥19 if immunocompromised). Pneumococcal for all PCV-naive adults ≥50 (one dose PCV20 or PCV21, or PCV15 then PPSV23), and ≥19 with risk conditions. RSV ≥75, and 50–74 at increased risk. COVID-19 per current ACIP. HPV through 26 (shared decision 27–45).

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