Uncomplicated UTI (cystitis) in women
What the major U.S. guidelines recommend, with a link to verify each at the source. A quick-reference summary for clinicians, not medical advice.
IDSA · 2011
First-line for uncomplicated cystitis: nitrofurantoin x5d, TMP-SMX x3d (if local resistance <20% and no recent use), or fosfomycin single dose. Avoid fluoroquinolones first-line (reserve for pyelonephritis).
Verify at IDSA →AUA · 2022
Recurrent UTI: consider non-antibiotic prophylaxis and limited self-start therapy; avoid routine post-treatment cultures if asymptomatic.
Verify at AUA →