Introduction Systematic developmental follow-up for children with congenital heart disease (CHD) is essential for the timely detection of developmental delays and disorders and to put in place the supports and resources necessary to maximise function and support family well-being. Best practice guidelines recommend follow-up for children with CHD at high risk of developmental delays. However, many countries, including Canada, have faced barriers such as limitations in financial and human resources which have limited their ability to implement these important neurodevelopmental follow-up…
Objectives This study examined temporal trends in physical fitness performance, body mass index (BMI) and physical activity behaviour among Swiss military conscripts from 2006 to 2024, including male conscripts and female volunteers, and explored differences by age, language region and urbanicity. Design Cross-sectional analysis of nationwide conscription data between 2006 and 2024. Setting Swiss Armed Forces conscription centres. Participants Records from 706 994 individuals (99.1% male conscripts and 0.9% female volunteers) were analysed. After exclusions for implausible anthropometric…
Purpose The Developmental Origin of Health and Disease framework emphasises the intergenerational influence of both maternal and paternal factors on the perinatal and longer-term outcomes of offspring. Aboriginal and Torres Strait Islander communities have driven major advances in family and health research across Australia, including longitudinal studies grounded in community priorities. Despite this progress, few birth cohort studies have focused on Indigenous families and even fewer have examined the health and well-being of Indigenous fathers. Participants The Indigenous Queensland Family…
Objectives To estimate the carbon footprint of a vaccine trial conducted in Uganda and to identify opportunities to reduce greenhouse gas emissions in future trials. Design Retrospective carbon footprint assessment of all trial-related activities conducted in Uganda (ClinicalTrials.gov ID NCT02991495), following the Greenhouse Gas Protocol and the guidance provided by the Low Carbon Clinical Trials Group. Setting The activities related to the yellow fever vaccine fractional dose trial implemented in Mbarara, with contributions from international collaborators. Participants The study assessed…
Introduction Antidepressant overprescribing and unnecessary long-term use are common and can increase the risk of adverse effects and withdrawal symptoms on discontinuation. Although gradual tapering strategies have been proposed, empirical evidence from randomised trials is lacking. This study will compare the efficacy of two antidepressant discontinuation strategies—linear and hyperbolic tapering—in adults with remitted depressive disorders. Methods and analysis This pragmatic, multicentre, open-label, parallel-group superiority randomised controlled trial will recruit adults (≥18 years)…
Objectives To describe preconception care health literacy among medical students and examine knowledge–behaviour gaps across academic years and by future parenthood intention. Design Cross-sectional online survey. Setting Kawasaki Medical School, Japan. Participants Medical students in years 1–6. A total of 613 students were included in the analysis. Primary and secondary outcome measures Preconception care health literacy was assessed using a validated Japanese preconception care-specific scale comprising a knowledge domain (13 true/false/do not know items; total score 0–13) and a…
Introduction Sodium-glucose cotransporter-2 (SGLT2) inhibitors were originally introduced for glycaemic management of type 2 diabetes mellitus and now provide substantial cardiovascular and kidney benefits. Although their association with genital mycotic infections is well established, whether SGLT2 inhibitor initiation increases the risk of symptomatic urinary tract infections (UTIs) remains uncertain, particularly within the cardiovascular-kidney-metabolic syndrome framework. This protocol describes a prospective multicentre observational study designed to address this clinically important…
In the Original Investigation titled “Hurdles for the Delivery of Multinational Randomized Clinical Trials,” published July 2, 2025, there was an error in Figure 1. Panel C (protocol approval to first patient in) originally listed the comparison as the pre–COVID-19 pandemic period vs the COVID-19 period. The comparison was between UK and non-UK countries during the COVID-19 pandemic period only. This article has been corrected.
This randomized clinical trial (RCT) explores whether messaging strategies incorporating behavioral economic principles increase enrollment fraction among Black and Hispanic patients in randomized clinical trials.
This qualitative study explores the perspectives of adults experiencing unsheltered homelessness who engaged in street-based treatment for hepatitis C virus.
This scoping review examines associations between water, energy, and food insecurities and health outcomes in South Africa and explores intermediate factors that may shape pathways between insecurities and health.
This cross-sectional study examines associations between digital health engagement within clinical care systems and psychological distress among US adults.
This cohort study evaluates whether sociodemographic and socioeconomic factors are associated with participation across stages in a risk-based lung cancer screening pilot program in Sweden.
This cohort study compares safety and quality outcomes of an advanced medical care at home program vs continued brick-and-mortar hospitalization for patients with acute heart failure.
This cohort study evaluates the safety, antitumor activity, and biomarkers associated with novel immunotherapy agents in patients with recurrent or metastatic head and neck squamous cell carcinoma treated in early-phase clinical trials.
Khong Guan Corporation (Union City, CA) is recalling specific lots of “Glutinous Rice Balls with Black Sesame Filling” and “Black & White Glutinous Rice Balls with Black Sesame Filling” in their recall expansion because they may contain undeclared peanuts. People who have an allergy or severe sensit
Digital health funding hit $7.4 billion in the first half of 2026, with megadeals absorbing nearly half of all capital. As AI becomes table stakes, founders and investors say the real differentiator is now domain expertise rather than technology. The post ‘The Moat is No Longer Technological’: How Digital Health Fundraising Changed in H1 appeared first on MedCity News .
Celcuity drug Revtorpyk is now approved for advanced cases of the most common type of breast cancer that do not harbor a certain mutation. The intravenously infused medicine is first in a new drug class that addresses a pathway associated with many cancers. The post Celcuity’s First-in-Class Drug Gets FDA Approval in Most Common Type of Breast Cancer appeared first on MedCity News .
The American Diabetes Association® (ADA) announces the release of its 2025 Annual Report mcarmody Wed, 07/15/2026 - 22:29 Organizational Updates The American Diabetes Association® (ADA) announces the release of its 2025 Annual Report Arlington, VA July 14, 2026 The American Diabetes Association® (ADA) announces the release of its 2025 Annual Report . This report highlights our impact across the ADA’s four strategic pillars of research, advocacy, education, and community connections. Person Name The ADA Press Team Email press@diabetes.org Phone 1-800-DIABETES (800-342-2383)