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The latest headlines across every section, pulled from official and open-access sources.

MedCity News · Aug 4, 2026

Pathos Picks Up Two Cancer Drugs Poised for Clinical Development With AI Agents

Pathos AI struck a deal for rights to a bispecific antibody drug conjugate from Alphamab that could become first in a new class of cancer drugs. Separately, the startup began a partnership with AstraZeneca on a protein degrader from the pharma company’s cancer drug pipeline. The post Pathos Picks Up Two Cancer Drugs Poised for Clinical Development With AI Agents appeared first on MedCity News .

ACC (Cardiology) · Aug 4, 2026

ATTR-CM: Sex Differences, Delayed Diagnosis and Effect of Acoramidis

Three recent studies, two published in JACC: Advances and a third published in JAMA Cardiology, investigate sex differences, delayed diagnosis and the effect of acoramidis on heart failure (HF)-related health status in patients with transthyretin amyloid cardiomyopathy (ATTR-CM).

ACC (Cardiology) · Aug 4, 2026

ADVANCE OUTCOMES: Ralinepag Reduces Clinical Worsening For PAH

Ralinepag, a selective prostacyclin IP receptor agonist, significantly reduced the risk of first clinical worsening compared with placebo in patients with pulmonary arterial hypertension (PAH) but was associated with more adverse-event-related treatment discontinuations, according to results of the ADVANCE OUTCOMES trial published July 28 in The Lancet.

ACC (Cardiology) · Aug 4, 2026

PARTNER 3: 7-Year TAVR vs. SAVR Outcomes in Low-Risk Patients

Both TAVR and SAVR were associated with a sustained, substantial improvement in patient-reported health status among patients with severe aortic stenosis (AS) considered at low risk, according to the seven-year outcomes of the PARTNER 3 trial published July 29 in JACC.

ACC (Cardiology) · Aug 4, 2026

JACC CKM Guideline Spotlight Issue Addresses Obesity, HF Prevention, More

The recent release of the 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome marked an important step in defining evidence-based approaches to CKM prevention, risk assessment and treatment.

MedTech Dive · Aug 4, 2026

Danaher promotes Julie Sawyer Montgomery to CEO

The executive has led Danaher’s diagnostics business, where she helped triple operating profit during her tenure and oversaw the recent acquisition of Masimo.

ACC (Cardiology) · Aug 4, 2026

Cardiogenic Shock and Mechanical Circulatory Support: Year in Review 2025

The year 2025 was a landmark year for cardiogenic shock (CS) and mechanical circulatory support (MCS). Two major clinical guideline documents were published, the longest-duration follow-up data from the field's pivotal trial were released, and real-world registries continued to challenge trial generalizability.

PLOS Medicine · Aug 4, 2026

Surgical palliative care: A multidisciplinary perspective on where we stand and how we need to evolve

by Samuel M. Miller, Paige DeGoursey, Kevin G. Billingsley Surgical palliative care (SPC) integrates the principles of symptom-based care and relief of suffering into traditional surgical practice. From the perspectives of a bedside nurse, surgical critical care fellow, and surgical oncologist, there are natural opportunities to incorporate these principles and in doing so, progress towards SPC becoming the standard of practice. From the perspectives of a bedside nurse, surgical critical care fellow and surgical oncologist, this Perspective by Samuel Miller, Paige DeGoursey and Kevin…

MedCity News · Aug 4, 2026

From Blind Spots to Better Outcomes: How SNF Data Transparency Strengthens LTSS

[Sponsored] What if health plans could identify member decline before an avoidable hospitalization occurs? Real-time clinical visibility into long-stay SNF members uncovers risk earlier and drives better outcomes. The post From Blind Spots to Better Outcomes: How SNF Data Transparency Strengthens LTSS appeared first on MedCity News .

BMJ Open · Aug 4, 2026

Cross-sectional analysis of knowledge, attitude and practice (KAP) on postoperative health self-management in patients undergoing percutaneous coronary intervention across different time intervals postprocedure at a tertiary hospital in China

Objectives This study aimed to investigate the knowledge, attitude and practice (KAP) regarding postoperative health self-management among patients undergoing percutaneous coronary intervention. Design A cross-sectional survey was conducted. Setting The study took place at Shanxi Bethune Hospital within the Department of Cardiology, encompassing both inpatient and outpatient settings. Participants A total of 500 patients who had undergone coronary interventional procedures participated in the survey. Interventions Demographic information and KAP scores were obtained using a self-administered…

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