PHILADELPHIA, May 11, 2026—Telemedicine can improve health equity by helping patients overcome barriers to in-person care, but meaningful policy changes are essential for lasting benefits, says the American College of Physicians (ACP). In a new paper, “ Telemedicine Policy and Practice: A Position Paper from the American College of Physicians ” published today in Annals of Internal Medicine , ACP issues recommendations for policymakers, regulators and health systems about how to improve telemedicine. ACP’s recommendations aim to ensure telemedicine is equitable, grounded in evidence, and used…
Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS. Author John Ravits, MD, of UC San Diego School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of ALS. Related Content: Amyotrophic Lateral Sclerosis Pridopidine in Amyotrophic Lateral Sclerosis What Is Amyotrophic Lateral Sclerosis? CNM-Au8 in Amyotrophic Lateral Sclerosis Safety and Efficacy of PrimeC in Amyotrophic…
by Silja Kosola Social media has evolved from connection to compulsion, disproportionately harming children and adolescents. Addictive designs together with developmental vulnerability fuel mental health risks and highlight the urgent need for stricter age limits and stronger protections. In this Perspective, Silja Kosola outlines how social media disproportionately harms child and adolescent mental health, and argues that while recent policy changes aimed at protecting youth from social media are welcome, stricter age limits and greater accountability of social media companies are needed.
FDA announced it is soliciting input on efforts with respect to drug repurposing to help address unmet medical needs across a range of diseases and conditions.
To the people of Tenerife, My name is Tedros, and I serve as the Director-General of the World Health Organization, the United Nations agency responsible for global public health. It is not common for me to write directly to the people of a single community, but today I feel it is not only appropriate, it is necessary. I want to speak to you directly, not through press releases or technical briefings, but as one human being to another, because you deserve that. I know you are worried. I know that when you hear the word “outbreak” and watch a ship sail toward your shores, memories…
FDA issued an approval for Bizengri (zenocutuzumab-zbco), a drug that treats NRG1 fusion-positive cholangiocarcinoma, an ultra-rare, aggressive cancer that forms in the bile ducts.
by Xiong-yu Liao, Hong Zheng, Jian-pei Fang, Dun-hua Zhou, Kun-yin Qiu Background Minimal residual disease (MRD) monitoring is a cornerstone of risk stratification in pediatric acute myeloid leukemia (AML), with a threshold of 0.1% conventionally defining positivity by flow cytometry. Advances in flow cytometric technologies, enabling detection of leukemic cells with higher sensitivity and specificity, warrant a reevaluation of whether a lower threshold improves prognostic accuracy. Methods and findings We conducted a retrospective cohort study using data from the Therapeutically Applicable…
by Gokul Parameswaran, Sadeer Al-Kindi, Sanjay Rajagopalan Climate change accelerates non-communicable diseases (NCDs) through cascading environmental disruptions and is attributed to driving increased NCD-related mortality. Yet this syndemic remains invisible and underfunded. We detail why addressing the climate-NCD intersection is critical for improving health. In this Perspective, Sanjay Rajagopalan and colleagues discusses how climate change accelerates non-communicable diseases (NCDs) and exacerbates NCD-related mortality, and calls for greater visibility and funding to address this…
The U.S. Food and Drug Administration today issued a final guidance for industry, Postapproval Pregnancy Safety Studies, with recommendations on different methodologies that can be used in the postapproval setting to study the safety of drugs and biological products when used during pregnancy.
The U.S. government is actively monitoring and responding to a hantavirus outbreak linked to the M/V Hondius cruise ship. At this time, the risk to the American public remains extremely low.
The U.S. healthcare sector accounts for roughly 8.5% of total greenhouse gas (GHG) emissions, driven largely by energy use, supply chains, transportation and waste. While much of the conversation about healthcare decarbonization has focused on hospitals and clinical care, health plans play a powerful—and often overlooked—role in shaping how care is delivered and how resources […] The post New NCQA Research: What Health Plan Leaders Can Do to Reduce Climate Impact appeared first on NCQA .
Dr Tedros Adhanom Ghebreyesus, WHO Director-General, briefed media today on a cluster of hantavirus cases linked to a cruise ship, the MV Hondius. Eight cases have been reported so far, including three deaths. Five of the 8 cases have been confirmed as hantavirus. The hantavirus involved is the Andes virus, the only species known to be capable of limited transmission between humans, linked to close and prolonged contact. Describing the situation, Dr Tedros said, “While this is a serious incident, WHO assesses the public health risk as low.” He noted that given the incubation…
FDA announced major steps in its bold initiative to modernize the agency. The agency launched Elsa 4.0, a significant upgrade to the agency’s internal AI tool available to all FDA staff, from scientific reviewers to investigators.
This week, we present research on high-risk coronary intervention strategies, targeted therapy for pancreatic cancer, an mRNA influenza vaccine, and treatments for severe scabies and sickle cell disease. We review cerebral amyloid angiopathy and follow a complex case of a disseminated infection. Perspectives address the impact of corporate medicine on medical training and drug pricing policy.
FDA announced that it is piloting one-day inspectional assessments, as part of a broader initiative to make its inspectional resources more targeted and efficient.
by Kira Elsbernd, Issa Sabi, Ilesh V. Jani, Chishamiso Mudenyanga, Siriel Boniface, Arlete Mahumane, Joaquim Lequechane, Falume Chale, Bindiya Meggi, Kassia Pereira, Raphael Edom, Anange F. Lwilla, W. Chris Buck, Nyanda Elias Ntinyinya, Michael Hoelscher, Till Baernighausen, Arne Kroidl, Stefan Kohler, the LIFE Study Consortium Background Timely access to early infant diagnosis (EID) is crucial for newborns with HIV, as late diagnosis can delay lifesaving antiretroviral treatment (ART). We assessed the comparative cost and cost-effectiveness of integrating point-of-care EID at birth into…
by Rami Subhi, Abiodun Sogbesan, Dan Muramuzi, Mikael Burhin, Ayobami A. Bakare, Adegoke G. Falade, Freddy E. Kitutu, Freddie Ssengooba, Carina King, Sumit Kane, Belinda Dawson-McClaren, Hamish R. Graham, the MOXY-Implementation Research Collaboration Background Child mortality remains high in countries with weak emergency care systems. Facility organisation for paediatric emergency care is heterogeneous and under-described. We examined how hospitals in Uganda and Nigeria are organised to deliver emergency care for neonates and children. Methods and findings We conducted a qualitative…
by Camila Bonfim, Flávia Alves, Maurício L. Barreto, Vikram Patel, Daiane Borges Machado Background Interpersonal violence is a significant public health issue, increasing mortality risks for those affected. While Cash Transfer Programs offer health benefits, their role in addressing the needs of interpersonal violence victims remains unclear. This study aims to examine the association between Brazil’s Bolsa Família Program (BFP) participation and reduced mortality rates among interpersonal violence victims. Methods and findings This cohort study was conducted using data from 100 Million…
Lack of Assurance of Sterility: This recall has been initiated due to CGMP deviations found by the FDA during an inspection of the manufacturer. — Thea Pharma, Inc. · Class II · Ongoing