Objective To assess the prevalence of discontinuation of short-term oral antibiotic therapy and to identify its predictors among patients attending outpatient department pharmacy units of public hospitals in Harar, Eastern Ethiopia. Design Facility-based prospective follow-up study. Setting All public hospitals in Harar, Eastern Ethiopia. Participants A total of 422 patients who received short-term oral antibiotics from Hiwot Fana Comprehensive Specialized Hospital (HFCSH) and Jugal General Hospital (JGH) from 20 January to 20 April 2024 were recruited using a systematic random sampling…
Introduction Rapid urbanisation, increasing housing density and rising costs have intensified pressure on urban housing systems, limiting access to health-promoting residential environments. Microhousing (compact units typically ranging from 15 to 40 m²) has emerged as a strategy to address these challenges. While microhousing improves affordability and spatial efficiency, it may also pose psychological and well-being challenges for residents. Salutogenic design, grounded in the sense of coherence framework, emphasises environmental resources that promote mental health and resilience…
Purpose The return to work after arthroplasty (REWARD) study was established to address knowledge gaps regarding factors influencing return to work and long-term workability following hip and knee arthroplasty. The study investigates how variables such as sex, occupational workload and prior treatments affect sick leave patterns across regions and healthcare providers in Sweden. By analysing trajectories of sick leave and disability pension before and after surgery, the study aims to identify determinants for successful return to work. Participants Initially, we identified two separate cohorts…
Introduction Surgical site infections (SSIs) impose a significant clinical and economic burden on the healthcare systems. To date, traditional preventive strategies have frequently failed to demonstrate definitive efficacy. Hypochlorous acid (HOCl) has emerged as a compelling antimicrobial alternative, characterised by potent microbicidal properties and excellent biocompatibility. Hypoclates:Peritonitis investigates the clinical impact of an HOCl-based lavage strategy in patients undergoing surgical treatment for secondary peritonitis. The trial evaluates the primary endpoint of postoperative…
Importance Day-of-surgery hyperglycaemia is a modifiable risk factor for adverse patient outcomes including infection and 30-day mortality. Despite these risks, important quality gaps in day-of-surgery glycaemic management have been demonstrated in multiple settings. Objective To describe barriers and facilitators to high-quality glycaemic management from the perspective of anaesthesiologists. Design This qualitative study was designed using two implementation frameworks, the Theoretical Domains Framework (TDF) and the Consolidated Framework for Implementation Research (CFIR), to understand…
Sales in Johnson & Johnson’s Abiomed business declined in the second quarter due to procedure volume pressures related to its Impella device.
Join SBIA as FDA shares the latest updates on registration and listing submissions, including current validation rules, and walks through the evolving regulatory requirements and compliance framework that shape how industry engages with these processes.
Jennifer Doudna, Ph.D., the Nobel Laureate best known for co-inventing the CRISPR system that has become the foundation for gene-editing, is dipping her toes into a new, buzzy field: AI-powered protein design.
Earlier this year, my colleague Matt Harrington suggested that clinical leaders should stop asking whether their organizations have an “AI strategy”, not because strategy doesn’t matter, but because the question often produces the wrong conversation.
We are moving into an era where we can finally converse with our data. We can ask, “Why are denials spiking in Region X?” or “Show me the safety profile of this cohort,” and receive an answer, not a spreadsheet. The post Answers at the Speed of Thought: Healthcare Analytics in the Era of Agentic AI appeared first on MedCity News .
In this week’s View, Dr. Eagle looks at the feasibility of mechanical leaflet splitting in high-risk patients undergoing valve-in-valve transcatheter aortic valve replacement (TAVR).
Letter about the pay round for the financial year 2027 to 2028 from the Secretary of State for Health and Social Care to the Review Body on Doctors’ and Dentists’ Remuneration (DDRB).
Letter about the pay round for the financial year 2027 to 2028 from the Secretary of State for Health and Social Care to the NHS Pay Review Body (NHSPRB).
Letter about the pay round for the financial year 2027 to 2028 from the Secretary of State for Health and Social Care to the Senior Salaries Review Body.
It appears Braveheart Bio isn’t going to let Big Pharma take its freedom anytime soon, as the company is aiming for a Nasdaq listing to move its phase 3 cardiovascular drug forward.
Medicines and Healthcare products Regulatory Agency (MHRA) has approved the use of UK‑donor plasma for five high‑priority plasma-derived medicinal products.
The FDA now treats continuous, real-time data sharing as a regulatory direction of travel rather than a theoretical future. The neurology field should pay close attention. The post The Measurement Problem Behind Two Decades of Neurology Trial Failures appeared first on MedCity News .
You cannot secure what you cannot see, and right now, healthcare organizations are accumulating hidden cyber liabilities with every keystroke. The post Off the Radar: How Unapproved AI Is Complicating Healthcare Cyber Risk appeared first on MedCity News .
Cases of iatrogenic botulism have been reported following the therapeutic or cosmetic use of botulinum toxin containing products where the toxin’s effect extends beyond the area of treatment. Patients should seek immediate medical advice if they experience signs and symptoms.
Lower BMI in older patients undergoing TAVR was associated with higher risk of all-cause mortality and major cardiovascular and cerebrovascular events at one year; however, outcomes did not differ between BMI groups among patients younger than 65 years old, according to a study published July 10 in JACC: Advances.