Background Acne vulgaris is a chronic inflammatory condition primarily caused by Cutibacterium acnes , which disrupts skin homeostasis, thereby triggering immune responses and sebum metabolism. Dysbiosis is an imbalance in the skin and gut microbiota identified as a significant factor contributing to acne progression. Standard therapy often relies on antibiotics, but the long-term use has increased antibiotic resistance, including in Indonesia. Consequently, alternative methods, such as probiotics and mesenchymal stromal cell secretomes, are gaining attention for immunomodulatory and…
Introduction Point-of-care technologies (POCTs) are essential to providing clinical care for patients, with their potential for rapid and accurate results on site supporting efficient clinical decision-making. Objectives To understand the current key needs, barriers and challenges of POCT developers for effective development and implementation of POCTs across diverse settings particularly in the domain of cancer, nutrition and infections. Design A qualitative semi-structured focus group discussion (FGDs) was employed. The FGDs were guided by the needs assessment process and the Phase Gate…
by Andrew S. C. Yuen, Kenneth K. C. Man Pain and fever in pregnancy require treatment, but fetal safety concerns complicate analgesic choice. A recent PLOS Medicine study presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but interpreting findings across studies is challenging. In this Perspective, Kenneth Man and Andrew Yuen highlight a recent PLOS Medicine study that presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but discuss why interpreting findings across studies is challenging.
by Yiran E. Liu, José Victor Bortolotto Bampi, Ronan F. Arthur, Argita D. Salindri, Caroline Busatto, Pedro Avedillo Jiménez, Daniele Maria Pelissari, Fernanda Dockhorn Costa Johansen, Robert Arana-Narvaez, Alvaro Fernando Moreno Roca, Wilfredo Santos Solís Tupes, Esther Mori Jiu, Christian Alfredo Moreno Roca, Erika Albertina Abregú Contreras, Valentina Antonieta Alarcón Guizado, Julián Trujillo Trujillo, Belkys Marcelino, Mónica Alonso Gonzalez, Mayra Cecilia Córdova Ayllon, Ted Cohen, Moises A. Huaman, Jeremy D. Goldhaber-Fiebert, Julio Croda, Jason R. Andrews Background Incarceration is a…
Millennials and Gen Z are more likely to engage earlier, seek care proactively, and continue treatment over time. A mental health diagnosis is more likely to represent active management, not a late-stage recognition of a problem that has already compounded. The post The Generational Inversion in Employer Health Costs That Most CFOs Aren’t Seeing appeared first on MedCity News .
MHRA’s Public Sector Equality Duty report 2026 sets out progress on equality, diversity and inclusion across regulation, public engagement and workforce.
Replacing a paper clipboard with a QR code on your phone doesn’t kill the clipboard; it’s just a better clipboard. Why? The burden is still on the patient. It’s the digital version of carrying a manila folder of records across town. This is a half-measure. It’s not true interoperability. The post Kill the Clipboard Tax appeared first on MedCity News .
AI can speed up drug discovery and decrease attrition rates in the clinic, but it is important to recognize that both are tall orders. The companies that will benefit most are those that stay grounded, set realistic expectations, and keep experienced scientists at the center of decisions that require genuine creativity and judgment. The post AI in Drug Discovery: Surveying the Breadth of the Challenges appeared first on MedCity News .
An urgent review led by Lord John Mann examining how the NHS, including employers and UK health regulators, identify, report and respond to antisemitism and other forms of racism.
[Sponsored] A checklist for AI readiness from Nordic aims to help healthcare organizations avoid failure. The post Is Your Healthcare Organization Ready to Implement AI? appeared first on MedCity News .
To collect and scrutinize millions of Americans’ health data, U.S. health secretary Robert F. Kennedy Jr. aims to work with state organizations that help health systems share medical records. In Nebraska, millions in federal dollars has flowed into one nonprofit cooperating with Kennedy’s project.