Latest medical news · page 267

FDA expands Lunsumio Velo (mosunetuzumab-axgb) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Genentech Inc

Risk Wire - Episode 3 - When Salmonella Crosses Borders

This is a third episode of our ECDC: On Air podcast sub-series - the "Risk Wire" - focusing on Risk Assessments ECDC publishes. This time we look into a prolonged multi-country outbreak of Salmonella Strathcona has affected 17 European countries and has been ongoing since 2023, with more than 400 confirmed cases reported so far. Investigations have identified small tomatoes as the most likely vehicle of infection, highlighting the complexity of foodborne outbreaks and the role of the environment in food contamination. In this episode, we talk to Dr Taina Niskanen, Expert in Food-, Waterborne…

WHO Guideline on the Use and Indications of GLP-1 Therapies for the Treatment of Obesity in Adults

Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease. WHO recently published a guideline in JAMA on the use and indications of GLP-1 therapies for the treatment of #obesity in adults. Francesca Celletti, MD, PhD, and Ezekiel Emanuel, MD, PhD, join JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss. Related Content: World Health Organization Guideline on the Use and Indications of Glucagon-Like Peptide-1 Therapies for the Treatment of Obesity in Adults

NEJM This Week — December 18, 2025

This week, we look at ctDNA-guided immunotherapy for bladder cancer, cardiovascular outcomes with tirzepatide, and evidence that one HPV vaccine dose may be enough. We explore high-dose rifampin for tuberculous meningitis, review measles amid rising outbreaks, and follow a challenging case of gastrointestinal bleeding. Essays examine how clinicians navigate post-Dobbs care, tobacco harm among people with mental illness, congenital syphilis, and sustaining medical research.

FDA expands Zynyz (retifanlimab-dlwr) approval

Efficacy supplement (new or revised indication). injectable, intravenous. Sponsor: Incyte Corp

FDA approves Exdensur (depemokimab-ulaa)

Original biologic license approval. injection. Sponsor: Glaxosmithkline Llc

Complications Associated With Transvenous Cardiac Implantable Devices

Dr. Centor discusses complications of cardiac implantable electronic devices with Dr. Peter Zimetbaum.

Head and Neck Cancer

Head and neck cancer is the seventh most common cancer worldwide and is commonly associated with tobacco and alcohol use, or human papillomavirus (HPV) infection. Author Lara Dunn, MD, of Memorial Sloan Kettering Cancer Center joins JAMA Associate Editor Margaret Wheeler, MD, to discuss the epidemiology, risk factors, diagnosis, treatment, and prognosis of head and neck cancer. Related Content: Head and Neck Cancer

Episode 243 -- December 2025 -- Part 1 AFP: American Family Physician

Cancer screening in older adults (1:30), an app for obstructive sleep apnea (5:10), nonsteroidal anti-inflammatory–induced ulcers and dyspepsia (7:20), hemorrhoids (10:00), late pregnancy bleeding (11:30), intensive glucose control in older patients (16:00), and all new holiday ICD-10 codes (19:30).

FDA expands Enhertu (fam-trastuzumab deruxtecan-nxki) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Daiichi Sankyo

FDA expands Ilumya (tildrakizumab-asmn) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Sun Pharma Global

FDA approves Lerochol (lerodalcibep-liga)

Original biologic license approval. injectable, injection. Sponsor: Lib Therapeutics, Inc.

AAFP urges feds to investigate downcoding as threat to primary care

CMS announces tech-driven alternative payment model

Episode 69 - A. Collins & G. Amore - Foodborne diseases: What’s really making you sick

In this episode of ECDC On Air, we are joined by Aine Collins and Giusi Amore - experts from ECDC and the European Food Safety Authority (EFSA) to unpack the latest EU One Health Zoonoses report. They discuss the main foodborne diseases in Europe, the everyday foods most often linked to outbreaks, and clear up common myths - from “it’s just food poisoning” to washing raw chicken or relying on the smell test. The conversation ends with simple, practical tips for safer food handling and storage at home. Want to learn more? -> Read our press release on the latest zoonoses report -> Read the full…

Two cases of Middle East respiratory syndrome (MERS) in travellers returning to France from the Arabian Peninsula

On 3 December 2025, the French Ministry of Health reported two imported human Middle East respiratory syndrome (MERS) cases with travel history to the Arabian Peninsula.

How Climate Change Affects Allergic Rhinitis and Sinusitis

Allergic rhinitis affects about 1 in 6 US adults. A recent JAMA Insights summarizes evidence regarding the associations of climate change and air pollution with allergic rhinitis and sinusitis. The discussion includes prevention and management strategies. Coauthor Neelima Tummala, MD, joins JAMA Deputy Editor Mary McDermott, MD, to discuss. Related Content: Climate Change, Allergic Rhinitis, and Sinusitis

Cost-Effectiveness of Weight Loss Drugs for Knee Osteoarthritis

Dr. Centor discusses the use of weight loss drugs to treat patients with knee osteoarthritis with Dr. David Felson.

Episode 242 -- November 2025 -- Part 2 AFP: American Family Physician

Vaginitis (1:20), gaming disorders (5:00), injections or radiofrequency for chronic back pain (8:50), developmental dysplasia of the hip (11:30), resistance training for cancer-related fatigue (15:00), and peripheral artery disease (17:10).

FDA approves Epysqli (eculizumab-aagh)

Original biologic license approval. injection, solution. Sponsor: Samsung Bioepis Co Ltd

FDA expands Imfinzi (durvalumab) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Astrazeneca Uk Ltd

FDA expands Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Genentech Inc

FDA expands Keytruda Qlex (pembrolizumab, berahyaluronidase alfa-pmph) approval

Efficacy supplement (new or revised indication). injectable, injection. Sponsor: Merck Sharp Dohme

FDA expands Keytruda (pembrolizumab) approval

Efficacy supplement (new or revised indication). solution, intravenous. Sponsor: Merck Sharp Dohme