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Latest medical news · page 219

The latest headlines across every section, pulled from official and open-access sources.

BMJ Open · Jun 4, 2026

Polyneuropathy in kidney transplant recipients: a cross-sectional study in Groningen, the Netherlands

Objectives To determine the prevalence and clinical characteristics associated with polyneuropathy in kidney transplant recipients (KTRs). Design Cross-sectional study. Setting SENS study at the University Medical Center Groningen, the Netherlands, December 2021–May 2023. Participants KTR, participating in the ongoing TransplantLines Biobank and Cohort Study, ≥12 months post-transplantation. Main outcome measures Participants underwent a structured neurological assessment including history taking, neurological examination, quantitative sensory testing and nerve conduction studies. An expert…

BMJ Open · Jun 4, 2026

Harms of selected spinal and paraspinal injections and denervation procedures for chronic non-cancer spine pain: a systematic review and meta-analysis of non-randomised studies

Objective To summarise the evidence on long-term and infrequent harms following selected spinal and paraspinal injections and denervation procedures for chronic non-cancer spine pain. Design Systematic review and meta-analysis. Data sources MEDLINE, EMBASE and Cumulative Index to Nursing and Allied Health Literature from inception to October 2023. Study selection Non-randomised studies reporting on harms of selected interventional procedures administered to adults living with chronic axial or radicular non-cancer spine pain with ≥4 weeks of follow-up. Data extraction and synthesis A…

BMJ Open · Jun 4, 2026

Suicides, suicide attempts and suicidal ideation among children and young people exposed to war: a scoping review

Objectives Worldwide, billions of children and young people live in areas affected by war. Suicide remains one of the three leading causes of death worldwide among people aged 15–29 years. However, little is known about the effect of war on suicidal behaviours in this group. This review aims to assess suicides, suicide attempts and suicidal ideation among children and young people exposed to war or armed conflict. Design A scoping review of studies was conducted using Web of Science, PubMed, Embase and PsycINFO databases from their inception to 18 November 2025, without any restrictions on…

BMJ Open · Jun 4, 2026

From victimisation to perpetration: a qualitative exploration of the lived experiences and perceptions of incarcerated women convicted of intimate partner violence in Maputo, Mozambique

Objective Numerous studies focus on women’s experiences of intimate partner violence (IPV), but there is a lack of qualitative studies focusing on women who, as victims, become perpetrators. The study explored the lived experiences and perceptions of incarcerated women convicted of IPV against their partner in Maputo, Mozambique. Design and setting A qualitative approach was utilised with females purposively sampled for one-on-one semi-structured interviews in the Maputo female prison setting. Data were analysed using Interpretive Phenomenological Analysis (IPA). Participants Nine females over…

BMJ Open · Jun 4, 2026

Mapping the current landscape of Klinefelter Syndrome registries: a scoping review

Objectives This scoping review identifies existing registries collecting data on Klinefelter’s syndrome (KS) patients and what data are collected, with the purpose of identifying any KS-specific registries. Findings to be used to inform future registry development. Design A comprehensive scoping review was conducted. Multiple sources were reviewed and articles screened based on inclusion criteria and exclusion criteria. Data sources Searches performed across multiple sources including PubMed, Embase, the Cochrane Library, WHO International Clinical Trials Registry Platform, Orphanet, EU…

BMJ Open · Jun 4, 2026

Oral probiotics and topical secretome to enhance clinical outcomes and microbiome restoration in acne vulgaris: a double-blind, randomised controlled trial protocol

Background Acne vulgaris is a chronic inflammatory condition primarily caused by Cutibacterium acnes , which disrupts skin homeostasis, thereby triggering immune responses and sebum metabolism. Dysbiosis is an imbalance in the skin and gut microbiota identified as a significant factor contributing to acne progression. Standard therapy often relies on antibiotics, but the long-term use has increased antibiotic resistance, including in Indonesia. Consequently, alternative methods, such as probiotics and mesenchymal stromal cell secretomes, are gaining attention for immunomodulatory and…

BMJ Open · Jun 4, 2026

Exploring the needs of technical developers and stakeholders in point-of-care technology development: a qualitative study

Introduction Point-of-care technologies (POCTs) are essential to providing clinical care for patients, with their potential for rapid and accurate results on site supporting efficient clinical decision-making. Objectives To understand the current key needs, barriers and challenges of POCT developers for effective development and implementation of POCTs across diverse settings particularly in the domain of cancer, nutrition and infections. Design A qualitative semi-structured focus group discussion (FGDs) was employed. The FGDs were guided by the needs assessment process and the Phase Gate…

PLOS Medicine · Jun 4, 2026

Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy

by Andrew S. C. Yuen, Kenneth K. C. Man Pain and fever in pregnancy require treatment, but fetal safety concerns complicate analgesic choice. A recent PLOS Medicine study presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but interpreting findings across studies is challenging. In this Perspective, Kenneth Man and Andrew Yuen highlight a recent PLOS Medicine study that presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but discuss why interpreting findings across studies is challenging.

PLOS Medicine · Jun 4, 2026

Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study

by Yiran E. Liu, José Victor Bortolotto Bampi, Ronan F. Arthur, Argita D. Salindri, Caroline Busatto, Pedro Avedillo Jiménez, Daniele Maria Pelissari, Fernanda Dockhorn Costa Johansen, Robert Arana-Narvaez, Alvaro Fernando Moreno Roca, Wilfredo Santos Solís Tupes, Esther Mori Jiu, Christian Alfredo Moreno Roca, Erika Albertina Abregú Contreras, Valentina Antonieta Alarcón Guizado, Julián Trujillo Trujillo, Belkys Marcelino, Mónica Alonso Gonzalez, Mayra Cecilia Córdova Ayllon, Ted Cohen, Moises A. Huaman, Jeremy D. Goldhaber-Fiebert, Julio Croda, Jason R. Andrews Background Incarceration is a…

MedCity News · Jun 4, 2026

The Generational Inversion in Employer Health Costs That Most CFOs Aren’t Seeing

Millennials and Gen Z are more likely to engage earlier, seek care proactively, and continue treatment over time. A mental health diagnosis is more likely to represent active management, not a late-stage recognition of a problem that has already compounded. The post The Generational Inversion in Employer Health Costs That Most CFOs Aren’t Seeing appeared first on MedCity News .

MedCity News · Jun 4, 2026

Kill the Clipboard Tax

Replacing a paper clipboard with a QR code on your phone doesn’t kill the clipboard; it’s just a better clipboard. Why? The burden is still on the patient. It’s the digital version of carrying a manila folder of records across town. This is a half-measure. It’s not true interoperability. The post Kill the Clipboard Tax appeared first on MedCity News .

MedCity News · Jun 4, 2026

AI in Drug Discovery: Surveying the Breadth of the Challenges

AI can speed up drug discovery and decrease attrition rates in the clinic, but it is important to recognize that both are tall orders. The companies that will benefit most are those that stay grounded, set realistic expectations, and keep experienced scientists at the center of decisions that require genuine creativity and judgment. The post AI in Drug Discovery: Surveying the Breadth of the Challenges appeared first on MedCity News .

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