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PLOS Medicine · Jun 12, 2026

Placenta accreta spectrum in the 21st century: Challenging dogma and redefining disorder

by Eric Jauniaux, Helena C. Bartels, Yalda Afshar Placenta accreta spectrum (PAS) is a serious pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux and colleagues discuss emerging evidence that challenges our long-held pathophysiological understanding of PAS, and argue that a critical reassessment of definition, diagnosis, and management is overdue. In this Perspective, Jonathan Evans and colleagues discuss why restricting access to joint replacement surgery based on BMI alone is not supported by evidence, and highlight how such rest…

PLOS Medicine · Jun 12, 2026

Comparison of count-based and clustering definitions of multimorbidity and their association with prevalence of multimorbidity, health profiles, and mortality: A cohort study of UK Biobank participants

by Gabriella C. Silva, Aurore Fayosse, Louis Jacob, Séverine Sabia, Archana Singh-Manoux, Benjamin Landré Background Multimorbidity, the presence of several chronic conditions, is linked to higher mortality and healthcare use and thus poses a major challenge for aging populations. While most studies rely on simple counts of conditions, clustering approaches have been proposed to describe patterns of co-occurring diseases. We aimed to evaluate the extent to which these methodological choices influence prevalence and association with health profiles and mortality. Methods and findings Using UK…

FDA Drugs · Jun 12, 2026

FDA Drug Competition Action Plan

FDA's Drug Competition Action Plan (DCAP) encourages robust and timely market competition for generic drugs and helps bring greater efficiency and transparency to the generic drug review process, without sacrificing the scientific rigor underlying our generic drug program.

MedCity News · Jun 12, 2026

Stop Presenting at Health-Tech Buyers — Let Them Drive

Winning in health-tech is about giving buyers enough operational clarity, early enough, that they can say yes with confidence rather than saying yes because the alternative is another six months of the same evaluation cycle. The post Stop Presenting at Health-Tech Buyers — Let Them Drive appeared first on MedCity News .

NCQA · Jun 12, 2026

Turning Data Into Action: A Playbook for Advancing Health Equity

Healthcare organizations across the country are committed to improving health equity—but many struggle with a fundamental question: how do you measure progress in a meaningful, actionable way? A new resource, Cracking the Code: A Health Equity Analytics Implementation Playbook for Healthcare Organizations, helps answer that question. The playbook offers a structured, practical approach for using […] The post Turning Data Into Action: A Playbook for Advancing Health Equity appeared first on NCQA .

FDA Drugs · Jun 12, 2026

Newly Added Guidance Documents

Guidance documents represent the FDA's current thinking on a particular subject. New guidance documents are listed here for three months.

EMA (EU) · Jun 12, 2026

Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 8-11 June 2026

PRAC concludes evidence of potential risk of neurodevelopmental disorders in children born to men treated with valproate is inconsistent  Committee recommends updating product…, Agenda Agenda of the PRAC meeting 8-11 June 2026Draft Reference Number: EMA/PRAC/115322/2026…, PRAC statistics: June 2026 , , Glossary Safety signal assessments. A safety signal is information which suggests a new potentially causal association, or a new aspect of a known association between…

MedlinePlus (NLM) · Jun 12, 2026

Vagus nerve stimulation

Source: Medical Encyclopedia Related MedlinePlus Pages: Depression , Epilepsy , Seizures

MedlinePlus (NLM) · Jun 12, 2026

GLP-1 agonists

Source: Medical Encyclopedia Related MedlinePlus Pages: Diabetes Medicines , Weight Control

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