UniQure is preparing to seek accelerated FDA approval for its Huntington’s disease gene therapy, a move that follows the FDA’s reversal of its prior position calling for another clinical trial. This gene therapy is the latest in a growing list of rare disease treatments to receive reconsideration from an FDA that appears to be swinging back to regulatory flexibility. The post FDA Reversal on uniQure Gene Therapy Is Another Sign of Renewed Regulatory Flexibility appeared first on MedCity News .
When information is everywhere, credibility is everything. The newly released Clarivate Journal Impact Factors reflect the broad global reach and influence of JACC and the entire JACC Journals family.
The Centers for Medicare and Medicaid Services (CMS) released a proposed decision memo on the National Coverage Determination (NCD) for TAVR, introducing changes to coverage pathways, evidence development and quality oversight.
Treatment of hypertension and hyperlipidemia was low among U.S. adults with cardiovascular-kidney-metabolic (CKM) syndrome, with less than half achieving blood pressure or glycemic control, and gaps in starting treatment were greatest among women, young adults and Hispanic adults. Furthermore, inadequate risk factor control was highest among those with the highest cardiovascular risk, according to research published June 17 in JACC.
Women who participate in resistance training (RT) may have a lower risk of cardiovascular disease, particularly myocardial infarction (MI), especially when combined with aerobic exercise, according to a large cohort study published June 17 in JACC.
Meet Ismael: Using His Voice for Change and a Better Future mseibold Wed, 06/17/2026 - 15:51 Type 1 Advocacy Share Your Story By sharing your story, you help us raise awareness of diabetes so we can bend the curve on it once and for all. Will you help us awaken the world? Share Your Story
Percentage of children immunised under the cover of vaccination evaluated rapidly (COVER) programme for quarter 4, from 1 January 2026 to 31 March 2026.
Deal volumes and values are tracking above the first half of 2025, driven by Boston Scientific’s Penumbra buyout and Danaher’s Masimo acquisition.
Combined upper and lower GI endoscopy is becoming standard practice across many US healthcare settings, but the quality infrastructure for upper GI has not kept pace with the procedures now being performed on it. The post Combined GI Procedures Are Becoming Routine – AI Can Help Address the Gap in Upper GI Quality Standards appeared first on MedCity News .
Objectives Composite indices provide an opportunity to measure the reach of multisector strategies as countries progress towards Sustainable Development Goals and the achievement of nutrition, health and other sectoral targets. Composite measures allow for the measurement of nutrition and health intervention coverage across sectors and can be used to benchmark progress, track nutrition goals and assess inequities of multisector nutrition interventions. Of the many composite indices in use to measure health and nutrition intervention coverage and population status as a means of assessing…
Objectives Frailty in people with heart failure (HF) is a multidimensional state and associated with poor outcomes. Addressing frailty in people with HF has been identified as a priority area to improve outcomes. Yet, related non-pharmacological interventions are rarely described in detail. The aim of this article is to map interventions and associated outcomes addressing frailty in people with HF across the physical-functional, clinical, psycho-cognitive and social dimensions of frailty. Design The scoping review is conducted according to the methodology of the Joanna Briggs Institute. Data…
Objective This study aimed to investigate the effects of different types of exercise on body composition in women with overweight or obesity and to compare the relative effectiveness of these interventions using a systematic review and network meta-analysis. Design Systematic review and network meta-analysis using the CINeMA (Confidence in Network Meta-Analysis) approach. Data sources PubMed, Embase, CINAHL, SportsDiscus, the Cochrane Library, Web of Science and Scopus were searched through September 2025. Eligibility criteria for selecting studies We included randomised controlled trials…
Introduction Pregnancy and childbirth are transformative experiences that can provoke anxiety, potentially reducing women’s confidence and satisfaction with the process. Systemic counselling, which considers family and interpersonal dynamics, may alleviate anxiety, enhance self-efficacy and improve satisfaction with childbirth. Addressing these psychological and relational factors is crucial for maternal and neonatal well-being. Methods and analysis This parallel-group randomised controlled trial will involve 72 primiparous pregnant women in Babol, Iran. Eligible participants will be randomly…
Introduction Autistic children can experience elevated levels of emotional and behavioural problems, which adversely impact their psychosocial functioning. Positive parenting behaviours can significantly shape children’s emotional and behavioural developmental trajectories. However, for autistic children, these parenting behaviours may vary depending on their social, sensory and intellectual profiles. Literature on the association between parenting behaviours and autistic children’s internalising and externalising symptoms has been mixed. Thus, the main objective of this study will be to…