Introduction The incidence of silent brain infarction (SBI) and perioperative neurocognitive disorders (PND) is higher in cardiac surgery. However, standard preventive strategies remain unknown due to limited evidence. Methods and analysis This multicentre, prospective, randomised controlled clinical trial with a 1-year follow-up includes patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB). 912 participants are randomly assigned 1:1 into either the intervention group with neuroprotective anaesthesia targets (mean arterial pressure 65–90 mm Hg, bispectral index 40–60…
Introduction Early childhood development (ECD) interventions support children aged 0–5 years, including those typically developing, at risk of delays or diagnosed with motor, cognitive, language or social-emotional disorders. Current assessments face barriers like limited access, high costs, intermittent evaluations and invasive methods. Voice offers a non-invasive digital biomarker, with artificial intelligence (AI) and machine learning (ML) enabling analysis of vocal features linked to developmental trajectories. This scoping review protocol synthesises evidence on AI-driven voice biomarkers…
Objectives Diabetes mellitus (DM) has a strong genetic component and is a known risk factor for several hand conditions. We aimed to examine whether DM in first-degree relatives is associated with an increased risk of hand surgical diagnoses. Design A retrospective cohort study. Setting Data were collected from a population-based cohort in southern Sweden (Malmö Diet and Cancer Study (MDCS)). Family relationships were obtained through the Swedish Multi-Generation Register and healthcare diagnoses from the National Patient Register. Participants 30 446 individuals (60% female) aged 45–73 years…
Objectives To identify risk factors and examine associations between colorectal cancer (CRC) status and modifiable and non-modifiable risk factors among patients diagnosed in Oman, considering the existence and increase of incidence and prevalence of these risk factors. Design A multicentre case–control study. Setting Sultan Qaboos University Hospital and the Royal Hospital in Muscat, Oman. Participants Patients diagnosed with CRC (n=166) and controls (n=166). Outcome measures A questionnaire adapted from the Colon Cancer Family Registry and other previously published studies was used to…
Introduction Infections are particularly common among hospitalised patients in surgical wards. Carbapenem antibiotics, major drivers of antimicrobial resistance, are frequently prescribed in this setting, often inappropriately and for unnecessarily prolonged durations. International guidelines emphasise the need for comprehensive multimodal antimicrobial stewardship programmes to optimise antibiotic use; however, evidence supporting their routine application in surgical wards remains scarce and is mostly derived from retrospective analyses or single-component interventions. This study aims to…
Background Muslim immigrants and their direct descendants are a large ethnoreligious minority in many regions, yet their access to palliative care remains under-researched and poorly theorised for practice. Existing evidence points to structural, communicative and cultural constraints, while mechanisms at the threshold of access remain unclear. Aim We explored access to palliative care among this population, developed an explanatory model of access dynamics and reconstructed culturally and religiously framed narrative resources. Design We conducted a qualitative, multicentre, four-group study…
Purpose Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative motor neuron disease (MND) with heterogeneity in disease onset, progression and treatment response. The Strategic ALS Australia–Systems Genomics Consortium (SALSA-SGC) was established in recognition of the need for large data sets of clinical data matched with biological samples to enable and foster ALS research and better understanding of aetiology and biological mechanisms. SALSA-SGC brought together the major Australian MND clinics to set up sustainable infrastructure that could facilitate long-term human…
CHICAGO, June 18, 2026 – MORNINGSTAR FARMS is voluntarily recalling two varieties of products in the U.S., Puerto Rico and Costa Rica because of possible plastic pieces in the food. Recalled varieties are: MORNINGSTAR FARMS Buffalo Chik’n Nuggets (10.5 oz) and MORNINGSTAR FARMS Hot & Spicy Sausage
Through a new partnership, Marathon employer clients who don’t currently offer Lantern’s specialty care benefit can purchase it directly through Marathon. The post Lantern, Marathon Health Launch Partnership to Provide Integrated Primary and Specialty Care appeared first on MedCity News .
Kardigan was able to upsize its IPO, raising more cash for three drug candidates in mid-stage clinical development for cardiovascular conditions with no available therapies. All three programs are expected to report key data in 2027 that could pave the way for Phase 3 testing. The post Kardigan’s IPO Lands $400M for Drugs That Get to Root Causes of Heart Diseases appeared first on MedCity News .
A recent JAMA editorial from two radiologists argues that elective whole-body MRI scan companies are misleading consumers about the benefits of said scans. The radiologists argue the MRIs are more likely to trigger harmful downstream procedures than they are to save lives. Not surprisingly, the three most prominent companies offering these scans denied the charge. The post Researchers Say Whole-Body MRI Companies Are Inflating the Scans’ Medical Benefits appeared first on MedCity News .
TAVR outcomes differ by sex and vary over time, with women seeing an early benefit with TAVR vs. SAVR that converged by year five and men exhibiting no significant differences across time points, according to a meta-analysis of nine randomized trials published June 10 in JACC: Advances.
FDA Commissioner's National Priority Voucher Program. The Commissioner's National Priority Voucher Program offers an unprecedented opportunity to reduce drug and biologic review times from 10-12 months to just 1-2 months.
In this episode, Chief Innovation Officer Dr. Ami Bhatt and Dr. Katie Berlacher discuss how large language models (LLMs) can be integrated into clinical workflows and medical education while preserving clinical autonomy.
June 18, 2026 - Clover Hill Dairy of Mechanicsville, Maryland is expanding their recall to include all Clover Hill Dairy brand cheese because it has the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, f