Introduction Mpox remains an ongoing global health concern, driven by an ongoing clade I outbreak in Central Africa, which has caused substantial morbidity and mortality. Despite deployment of the Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine, data on the durability of vaccine-induced immune responses remain limited, particularly in African populations, women and people with HIV, highlighting the need for context-specific immunogenicity data. Methods and analysis Mpox-Vax AFRIVAC is a prospective, multicentre observational cohort study conducted in Uganda, Tanzania and the…
Background Lactational mastitis is a common inflammatory condition that can adversely affect maternal well-being and is associated with early cessation of breastfeeding. Although antibiotics and analgesics are widely used in clinical practice, concerns regarding antimicrobial resistance and potential effects on the infant microbiome have prompted increasing interest in non-pharmacological approaches. A range of physical and biological interventions, including probiotics, therapeutic ultrasound, acupuncture and manual therapies, have been investigated; however, the comparative effectiveness and…
Introduction Afghanistan has experienced decades of war, political instability, displacement, poverty and structural upheaval, all of which are likely to have contributed to the population’s deteriorating mental health. Individual studies and reports describe depression, anxiety, trauma-related distress and a severe lack of access to care, especially among women. However, the evidence remains fragmented. There has been no recent synthesis of evidence on mental health conditions, determinants, coping strategies, services and interventions among people living in Afghanistan. This protocol…
Introduction Continuity of care with a family physician (FP) is a core attribute of effective primary care and is associated with improved health outcomes, reduced service use and lower healthcare costs. In Canada, an ageing FP workforce has led to an increasing number of patients losing their FP, raising concerns about access to care and disruptions in care trajectories. While the benefits of continuity are well documented, evidence on the consequences of discontinuity in primary care, particularly from the patient perspective, remains limited. Relational discontinuity occurs when there is a…
Not content with navigating Rezdiffra’s trajectory to blockbuster territory, Madrigal Pharmaceuticals has spent 2026 shopping for a range of drugs that the company hopes could work alongside its metabolic dysfunction-associated steatohepatitis trailblazer.
Function Health raised $450 million in growth financing from General Catalyst’s Customer Value Fund, just eight months after its $298 million Series B. The lab-testing startup plans to use the capital to expand access to its testing and imaging services. The post Why General Catalyst Is Betting $450M on Function Health’s Preventive Care Push appeared first on MedCity News .
Findings from ASCOF, which measures how well care services achieve outcomes including quality of life and whether long-term support needs are being met.
North Carolina's Robeson County, where most of the tribe’s citizens live, ranks as one of the worst counties in the U.S. for health disparities. After securing federal recognition, Lumbee tribal leaders will have to decide how to address them.
They’re known for touting pandemic precautions, Affordable Care Act plans, and testing for lead in schools. This year, some former public health officials are touting themselves — for governor or senator.
A phase 3 trial of Novo Nordisk’s ziltivekimab has missed its primary endpoint, denting the prospects of a molecule analysts tipped to generate blockbuster sales and diversify the company’s portfolio. Novo has chances to rescue the program with its ongoing Artemis and Hermes trials.
Official statistics on the deferred payment agreements (DPAs) that local authorities have arranged with clients to help with the payment of the costs of their care.
The importance of continuity between midwifery and health visiting services in England, and how this helps families receive safe, high-quality perinatal care.
Failure of an electrical component in certain Astral ventilators may cause an interruption or failure in therapy which may result in serious injury or death.