Introduction Guideline-directed medical therapy (GDMT) has been demonstrated to reduce morbidity and mortality in patients with heart failure (HF). In addition to the need for GDMT, a large number of cardiovascular and non-cardiovascular medications are prescribed to patients with HF, especially the elderly, due to multiple comorbidities and chronic health conditions, such as chronic pain, musculoskeletal problems, insomnia or gastrointestinal issues. Polypharmacy may reduce adherence to GDMT and compromise its optimisation, potentially leading to worse clinical outcomes in patients with HF…
Background and objectives Clinical trials are essential for advancing scientific knowledge and improving patient outcomes. In the last decade, Bahrain has made notable progress in healthcare. However, clinical trial participation from the region remains modest. Thus, our study aimed to explore the perspectives of key opinion leaders on the challenges and potential solutions to conducting clinical trials in Bahrain. Design We conducted an exploratory qualitative study with key opinion leaders involved in clinical trials in Bahrain. Data were analysed using Braun and Clarke’s six-step thematic…
Introduction The efficacy of guideline-directed medical therapy (GDMT) for heart failure has been established in clinical trials, but trial populations differ substantially from real-world clinical practice. Consequently, the real-world status of GDMT implementation, the patient-level factors that determine whether guideline-recommended targets are achieved and the clinical circumstances that limit optimisation remain poorly characterised. We designed the Observational Multicenter Registry to Update Key Interventions and New Approaches with Artificial Intelligence for Heart Failure registry, a…
Objective This study aimed to describe the knowledge, attitudes and practices of emergency department (ED) doctors regarding regional analgesia (RA) for hip fractures and to compare these across levels of experience. Design A prospective, multicentre survey-based cross-sectional study. Setting Surveys were collected at the EDs of three university-affiliated hospitals in Johannesburg, South Africa. Participants 80 surveys were collected. Participants included all ED doctors. Doctors completing their internship years were excluded. Primary and secondary outcomes The primary objectives of this…
Objectives This external pilot study aimed to evaluate whether a definitive trial of the STAIR OF KNOWLEDGE intervention is warranted. The specific outcomes concerned the trial procedure, including the recruitment, randomisation and retention of nursing homes and the clinical outcomes required for a definitive trial. Design The study is an external pilot cluster randomised controlled trial. Setting Swedish nursing homes participated. Participants The inclusion criteria for participation in the study were nursing homes working with in the Swedish national quality registry Senior Alert. Data…
Objective To assess services provided by, and barriers to, hospital-based one-stop centre (OSC) services for women survivors of sexual violence in Ethiopia. Design A mixed-methods study integrating quantitative service data with that from qualitative interviews. Setting Hospital-based OSCs in Addis Ababa, Ethiopia. Participants Hospital records of 2283 female survivors, in-depth interviews with 20 survivors and 17 key informants. Results Quantitative analysis of hospital records showed the majority (61.9%) of survivors seeking OSC care did so within 72 hours of experiencing sexual violence…
Objectives This study aimed to explore the perceptions of Australian healthcare providers (HCPs) of the usefulness of smart inhalers for children with asthma and considerations for their effective integration into routine care. Design Qualitative descriptive study using semi-structured interviews. A hybrid thematic analysis approach was used to analyse the data. Setting Healthcare services in Australia including general practice, hospitals and Local Health Districts. Participants Eight general practitioners, six paediatric specialists and nine respiratory nurses were recruited using a unique…
Utilization — not cost growth — continues to accelerate spending, government actuaries said. Spiking prescription drug spending, including on GLP-1s, is especially acute.
Patient group direction (PGD) template to support the national meningococcal group B (Bexsero®) vaccination one-off, time-limited offer Autumn 2026 programme.
by Tyler Y. Headley, Yesim Tozan Background Global armed conflict and population displacement are increasing, yet their association with population health remains poorly understood. We developed and tested four theoretical models linking armed conflict, population displacement, and socioeconomic development to measles burden across 193 countries from 2000 to 2023. Methods and findings We analyzed longitudinal country-level data comprising 4,632 country-year observations, combining fixed-effects panel regression and structural equation modeling (SEM). Observed variables included battle-related…
AI isn’t failing because it lacks capability. It’s failing because it isn’t consistently reaching the moments where decisions are made. The post Why Most Healthcare AI Fails After the Pilot Phase appeared first on MedCity News .
Bear Stewart LLC of Chicago, IL is voluntarily recalling a single lot of Bakr Brown Butter Chocolate Chunk Ready To Bake Cookie Dough pouches because it may contain undeclared soy. People who have an allergy or severe sensitivity to soy run the risk of serious or life-threatening allergic reaction i
For years the healthcare system has relied on the slow machinery of research — and that system is failing the people it was built for. It was designed for a world that operated with an abundance of caution and lacked the modern tools of today. That world no longer exists. The post Real-Time Trials Are Here — Now We Need Real-Time Trust appeared first on MedCity News .
When education is incomplete, patients don’t just feel uninformed; they feel dismissed. The post Where Patient Education Breaks Down in Breast Cancer Care appeared first on MedCity News .
[Sponsored] Give us a few minutes of your time for our survey and we’ll make it worth your while! The post How Are Payers and Providers Thinking of AI and Cybersecurity? appeared first on MedCity News .
Alfalfa sprouted seeds have been identified as the likely source of a multi-country outbreak of Salmonella Bovismorbificans infections, according to a Rapid Outbreak Assessment published by EFSA and ECDC.
You can now register to attend this year’s European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE), taking place in Stockholm and online on 18–20 November 2026. Registration is free of charge.
You can now register to attend this year’s European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE), taking place in Stockholm and online on 18–20 November 2026. Registration is free of charge.