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The latest headlines across every section, pulled from official and open-access sources.

BMJ Open · Jul 7, 2026

Mental health outcomes and psychosocial correlates among adult members of business families in Germany (WIFU-GESUND): study protocol for a representative cross-sectional study

Introduction Mental health is an urgent public health issue with social and economic relevance. Business families play a key economic role, yet their specific mental health challenges remain underexplored. High performance expectations, succession pressures and the wish for discretion may obscure psychological stress. The WIFU-GESUND study addresses this gap by conducting the first representative mental health survey among adult members of business families in Germany. Methods and analysis This cross-sectional study targets adults with legal ownership in German family businesses. A…

BMJ Open · Jul 7, 2026

Multidimensional correlates of adherence to cardiovascular treatment among patients with multimorbidity from tribal communities in South India: an exploratory cross-sectional study

Introduction Tribal people in India face a growing risk of multimorbidity, primarily from cardiovascular diseases (CVD) due to changing lifestyles and unique socio-cultural and political factors. We aimed to identify treatment patterns and barriers to medication adherence for CVD. This will inform culturally sensitive implementation strategies that may improve outcomes among tribal communities. Methods We conducted an exploratory cross-sectional study among participants with multimorbidity in a South-Indian tribal setting. We used a structured questionnaire, guided by the Consolidated…

BMJ Open · Jul 7, 2026

Guangxi Eco-Environmental Health and Aging Study (GEHAS)

Purpose The Guangxi Eco-Environmental Health and Aging Study (GEHAS) was established to investigate the interplay between eco-environmental exposome, multi-omics profiles, and healthy ageing in a multi-ethnic subtropical population. This prospective cohort was designed to address knowledge gaps regarding how eco-environmental and lifestyle factors influence ageing trajectories. Participants GEHAS enrolled 5645 participants (59.8% women; mean age 62.51 years) from Guilin, Guangxi, at baseline, with Yao and Han participants accounting for 60.3% and 36.2% of the cohort, respectively. Baseline…

BMJ Open · Jul 7, 2026

Understanding citizens preferences for prioritising patients in the face of scarce surgical capacity in the Netherlands: a think-aloud study

Objectives Scarce surgical capacity makes prioritisation decisions unavoidable. During crises, the complexity and societal sensitivity of such decisions become particularly evident, underscoring the importance of engaging multiple stakeholders, including citizens. Citizens may hold different preferences and attach importance to different considerations than physicians regarding what is fair or appropriate when allocating scarce surgical capacity. This study, therefore, examined which preferences and considerations citizens consider important in decisions about prioritising patients for limited…

BMJ Open · Jul 7, 2026

Clinical, procedural and patient-reported outcomes of the Ultimaster Nagomi sirolimus-eluting coronary stent in complex percutaneous coronary intervention: the NAGOMI COMPLEX prospective cohort study protocol

Introduction Percutaneous coronary intervention (PCI) has evolved significantly over the past decade with approximately 30% of patients presenting with complex coronary artery disease, posing heightened procedural and long-term risks. Complexity in PCI is increasingly recognised as multifactorial, encompassing lesion, procedural and patient-related characteristics. The Ultimaster Nagomi sirolimus-eluting coronary stent system is designed to address the challenges of complex PCI. The NAGOMI COMPLEX study aims to assess its safety and clinical performance in a comprehensively defined complex PCI…

BMJ Open · Jul 7, 2026

Perceptions and experiences of patients with stable coronary heart disease participating in shared decision-making: a qualitative study in China

Objectives To explore, from the perspective of patients with stable coronary artery disease (SCAD), their perspectives and experiences of shared decision-making (SDM) participation. Design A descriptive qualitative research design was adopted in this study. The reflexive thematic analysis method was used to generate themes. Setting The study was conducted at a grade III level A hospital in Hangzhou, Zhejiang Province, China. The main interview locations for this study were quiet wards, meeting rooms and the respondents’ residences. Participants Between January and April 2025, 15 patients with…

BMJ Open · Jul 7, 2026

Neighbourhood environments, structural inequities, and colorectal cancer risk and mortality: analysis from the Southern Community Cohort Study

Objective Neighbourhood socioeconomic status (nSES) and built environment features strongly influence diet, physical activity and cancer screening adherence, potentially affecting colorectal cancer (CRC) incidence and prognosis. The aim of this study is to assess the association between neighbourhood obesogenic environments (eg, nSES, restaurant and retail food indices, recreational facilities, and business district residence) and CRC risk and mortality. Design A secondary data analysis was performed using prospectively collected data from the Southern Community Cohort Study. Setting 12 states…

BMJ Open · Jul 7, 2026

Abscopal responses following stereotactic ablative radiotherapy during immune checkpoint inhibitor therapy in metastatic renal cell carcinoma: protocol for the prospective multicentre observational AURICRE study in Japan

Introduction Patients with metastatic renal cell carcinoma (mRCC) treated with immune checkpoint inhibitors (ICIs) may experience immune-confirmed stable disease (iSD) or progressive disease (iCPD). Abscopal responses following ultra-hypofractionated radiotherapy during immunotherapy have been reported, but their incidence, timing and associated clinical or biological factors remain poorly defined in prospective observational settings. Methods and analysis AURICRE is a prospective, multicentre observational study that plans to enrol 145 patients with mRCC who exhibit iSD or iCPD during ongoing…

BMJ Open · Jul 7, 2026

Outcomes at school-age of children born extremely preterm or extremely low birth weight in Victoria, Australia: protocol for the 8-9 years follow-up of the prospective, longitudinal Victorian Infant Collaborative Study (VICS) 2016-2017 cohort

Introduction Children born extremely preterm (EP; <28 weeks’ gestation) and/or extremely low birth weight (ELBW; <1000 g) are at increased risk of difficulties across a range of neurodevelopmental domains and respiratory outcomes long term. The Victorian Infant Collaborative Study (VICS) in Australia has tracked detailed perinatal and developmental outcomes across four distinct EP/ELBW birth cohorts: 1991–1992, 1997, 2005 and 2016–2017. Improvements in 2-year developmental outcomes were reported in the VICS 2016–2017 cohort compared with previous eras; however, whether these improvements are…

BMJ Open · Jul 7, 2026

Rapid sequence induction versus standard induction in patients with moderate aspiration risk: study protocol for a multicentre randomised controlled trial (INCORRECT trial)

Introduction Rapid sequence induction (RSI) is widely used in patients at risk of pulmonary aspiration but may be associated with haemodynamic instability and intubation difficulties. It remains unclear whether patients with moderately increased risk of aspiration benefit from RSI compared with standard induction including mask ventilation. Methods and analysis This multicentre, randomised, controlled, parallel-group, patient-blinded trial will enrol 792 adult surgical patients with moderately increased risk of aspiration. Participants will be randomised 1:1 to RSI (no mask ventilation…

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