The Clinical Times
The Front Page of Medicine

Medical Technology · page 5

Devices, digital health, and the technology changing how care is delivered.

Fierce Biotech

GLP-1s may combat depression by multiplying a mood-boosting gut microbe

Since GLP-1 drugs like Novo Nordisk’s semaglutide and Eli Lilly’s tirzepatide took the world by storm for their potent treatment of diabetes and obesity, they have also been plagued by a clinical conundrum. In some studies, the peptides seem to possess antidepressant effects, while in others they’ve been linked to worse mental health and even increased suicidality.

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