Guidelines & Practice · page 4

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CDER Guidance Agenda

CDER Guidance Agenda

New WHO guidelines: up to 45% of dementia risk could be prevented or delayed

The World Health Organization (WHO) today released updated guidelines on reducing the risk of cognitive decline and dementia , providing countries with evidence-based recommendations to help prevent or delay the onset of dementia across the life course. Dementia is a condition caused by brain diseases and affects memory, thinking and the ability to function. More than 57 million people live with dementia worldwide and nearly 10 million people get newly diagnosed every year. Alzheimer disease is the most common form of dementia and is estimated to account for 60–70% of cases. While there…

2026 Care of the Athletic Heart Take-Home Points

The 2026 Care of the Athletic Heart was a 1-day preconference held in advance of the American College of Cardiology Annual Scientific Session. The session, hosted by Dr. Jeffrey Hsu, welcomed guests from over 14 countries and aimed to deliver focused, practical updates in sports cardiology, while providing education and insight into this rapidly evolving field.

ACP says underregulated dietary supplements endanger public health

PHILADELPHIA, July 13, 2026—Dietary supplements must be more regulated to protect public health, says the American College of Physicians (ACP). In a new paper, “ Modernizing the Regulatory Framework for Dietary Supplements: A Position Paper from the American College of Physicians ” published today in Annals of Internal Medicine , ACP issues recommendations to strengthen and modernize the manufacturing and marketing of dietary supplements. Over half of adults in the United States consume dietary supplements, but only one quarter consume supplements that have been recommended by a health care…

ACC, Other CV Societies Urge Withdrawal of OMB Research Funding Proposal

The ACC, joined by the American Society of Echocardiography, the American Society of Nuclear Cardiology, the Society for Cardiovascular Angiography & Interventions, and the Society of Cardiovascular Computed Tomography, has submitted comments to the Office of Management and Budget (OMB) expressing significant concerns with proposed revisions to the Uniform Guidance governing federal financial assistance programs.

Safety of Antiarrhythmic Agents in Breastfeeding Women

According to the American Academy of Pediatrics (APA) and the World Health Organization (WHO), exclusive breastfeeding is recommended for the first 6 months of infant life, with continuation up to 2 years or as long as mutually desired by the lactating individual and infant.

Proposed changes to federal research grants could interfere with grant dissemination, research accessibility

ACP expressed its concerns with the proposed changes to the Office of Management and Budget and urged the agency to revise the proposed rule.

Meet Melanie: Finding Freedom, Confidence, and a New Normal with Type 1 Diabetes

Meet Melanie: Finding Freedom, Confidence, and a New Normal with Type 1 Diabetes mseibold Fri, 07/10/2026 - 15:23 Type 1 Share Your Story By sharing your story, you help us raise awareness of diabetes so we can bend the curve on it once and for all. Will you help us awaken the world? Share Your Story

ACIP, MMRV, and Vaccine Equity

Public Health

Modest sleep loss linked to weight gain in adults with high cardiometabolic risk

Exploring the effect of 6 weeks of sleep restriction (SR) of 1.5 hours per night on energy balance and body weight regulation.

Novel TEER System Safe, Effective For High-Risk Primary MR Patients

For high-risk patients with primary mitral valve regurgitation (MR), the novel Neonova transcatheter edge-to-edge repair (TEER) system was safe and effective, with a high rate of event-free survival and sustained clinical and echocardiographic improvements through two years, according to a prospective study published June 29 in JACC: Asia.

Joint Society Editorial Calls For Science-Based Approach to CV Health Equity

A joint editorial on behalf of the ACC, American Heart Association, European Society of Cardiology and World Heart Federation calls for a new era of equity-centered cardiovascular care designed to redefine prevention, optimize care delivery and ensure that all patients worldwide benefit equally from the promise of modern cardiovascular medicine.

SHaRe Registry Identifies MACE Predictors in Mild HCM

About one in five patients with phenotypically mild hypertrophic cardiomyopathy (HCM) experienced major adverse cardiovascular events (MACE) over seven years of follow-up, according to SHaRe Registry research published July 8 in JACC.

Recent Actions and Updates From the American Diabetes Association

Recent Actions and Updates From the American Diabetes Association mcarmody Wed, 07/08/2026 - 17:10 Organizational Updates Recent Actions and Updates From the American Diabetes Association Arlington, VA July 8, 2026   Since the CEO of the American Diabetes Association® (ADA),  Charles “Chuck” Henderson, issued an apology —taking responsibility for missteps at the 2026 Scientific Sessions and personally apologizing to the five scientists by name—the ADA Executive team and Board of Directors have begun a comprehensive assessment of our practices, processes, and organizational approach…

PFA Matches RFA on PVI Durability, Shows Low AE Rates in Registry Data

Two studies published in JACC: Clinical Electrophysiology on June 29 provide new insights on the durability of pulmonary vein isolation (PVI) with pulsed field ablation (PFA) vs. radiofrequency ablation (RFA) in patients with persistent atrial fibrillation (AFib), as well as the safety profile of PFA among patients undergoing their first ablation for AFib.

Eagle’s Eye View: Can Sugar-Sweetened Beverages and Fruit Juice Lead to Hypertension?

In this week’s View, Dr. Eagle looks at withdrawing guideline-directed medical therapy (GDMT) for patients with atrial fibrillation (AF).

Guidance Recap Podcast | Assessing the Effects of Food on Drugs in INDs and NDAs – Clinical Pharmacology Considerations

Guidance Recap Podcast | Assessing the Effects of Food on Drugs in INDs and NDAs – Clinical Pharmacology Considerations

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Mechanical Leaflet Splitting is Feasible in High-Risk Patients Undergoing Valve-in-Valve TAVR

Mechanical leaflet splitting in patients with anatomically high-risk undergoing valve-in-valve (ViV) TAVR saw high procedural success, according to a study published June 25 in JACC: Cardiovascular Interventions.

Antihypertensive Medications in Pregnancy and Lactation: A Practical Approach

Effective management of hypertensive disorders of pregnancy is critical to reducing maternal morbidity, improving fetal outcomes, and mitigating long-term cardiovascular risk. This review provides a practical framework for antihypertensive medication selection in pregnancy and the postpartum period.

Accelerated Aging in the Adult Congenital Heart Disease Population

Aging is a major risk factor for most diseases, and accelerated biological aging is increasingly recognized in many chronic diseases. Chronological age refers to the time that has elapsed since birth, whereas biological age reflects functional, cellular, and tissue age.

NICE recommends Endosure and Endotest diagnostics for endometriosis

Women in England are set to gain new, taxpayer-funded tests for endometriosis after NICE recommended them for regular use.

GetWell Integrative Health

GetWell Integrative Health Anonymous (not verified) Fri, 07/03/2026 - 11:01 Program Name GetWell Integrative Health Accepting Referrals from RH 1 Address 701 Ave. Ponce de Leon Suit 108-A San Juan , PR 00907 United States Geocoding Field POINT (-66.083423 18.456213) Phone 787-556-3021 Program Type DPPE Record Type 012Rk00000MXcjPIAT Delivery Mode In-person Accepts Medicare 0 Program Id DPPE-644 DP Alliance Program c 1