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Guidelines & Practice · page 11

Practice updates and recommendations from the major professional societies.

ACC (Cardiology)

Poll: Brainstorm: Restarting Anticoagulation After Brain Bleed

An 80-year-old man presents for a cardiovascular follow-up after a prolonged hospitalization in the setting of an intracerebral hemorrhage. His medical history is relevant for atrial fibrillation, stage 3b chronic kidney disease, heart failure with preserved ejection fraction, hypertension, myocardial infarction 10 years ago, and type 2 diabetes mellitus.

ACC (Cardiology)

EWAS Identifies Associations Between DNA Methylation, Atherosclerosis

An epigenome-wide association study (EWAS) identified a large number of associations between DNA methylation and carotid, coronary and peripheral atherosclerosis, with >90% of sites traceable to the epigenetic signatures of cardiovascular risk factors, predominantly smoking, according to research published June 3 in JACC.

ACC (Cardiology)

ACC CardiaCast: Diagnosing PSVT

This episode is part of ACC’s ongoing effort to improve recognition and diagnosis of arrhythmias in clinical practice. In this CardiaCast, faculty explore a modern approach to identifying paroxysmal supraventricular tachycardia (PSVT), with a focus on real-world diagnostic challenges.

ACC (Cardiology)

First-Ever Guideline Addresses CKM Syndrome

The new 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome is the first ever to address the "interrelated condition characterized by the interconnections among metabolic risk factors (including obesity and type 2 diabetes)...

ACC (Cardiology)

SOGALDI-PEF: Baseline Renin Levels Predict BP Treatment Effect

Patients with low plasma renin levels had a more pronounced blood pressure (BP) reduction with spironolactone/dapagliflozin vs. dapagliflozin alone, in addition to seeing a more favorable impact on cardiovascular structure and function, while aldosterone levels exhibited no predictive value in treatment response...

ACC (Cardiology)

Follow-Up of FAVOR III Suggests QFR-Guided PCI Improves 5-Year Outcomes

When compared with angiography guidance, quantitative flow ratio (QFR)-guided PCI improved five-year clinical outcomes with benefits primarily achieved in the first two years, according to a follow-up study of the multicenter, sham-controlled FAVOR III trial published June 10 in JACC.

ACC (Cardiology)

CLASP IID: Residual MR and Gradient at 1 Year Post M-TEER

Patients who underwent mitral transcatheter edge-to-edge repair (M-TEER) with an optimal result were more likely to have improved hemodynamics and less likely to experience major adverse events, all-cause mortality, heart failure (HF) hospitalization or reintervention at one year...

ACC (Cardiology)

LOGICAL: Conservative Oxygen Therapy Fails to Improve Survival Outcomes After Cardiac Arrest

When compared with liberal oxygen therapy, conservative oxygen therapy did not improve rates of survival with favorable functional outcomes among unresponsive patients in the intensive care unit (ICU) receiving mechanical ventilation after cardiac arrest, according to results from the investigator-initiated, open-label LOGICAL trial published June 10 in NEJM.

ACC (Cardiology)

VitaK-CAC: Menaquinone-7 Attenuates CAC in CAD

Supplementation with the vitamin K homologue menaquinone-7 (MK-7) significantly attenuated coronary artery calcification (CAC) compared with placebo in adults with symptomatic coronary artery disease (CAD), according to research published June 10 in JAMA Cardiology.

ACC (Cardiology)

CAMERA-MRI II: Catheter Ablation in Patients With AFib and LVSD by LGE Status

In patients with atrial fibrillation (AFib) and left ventricular systolic dysfunction (LVSD), catheter ablation was associated with substantial improvement in LVEF regardless of late gadolinium enhancement (LGE) status, while 12-month LVEF and normalization rates were lower in patients with LGE present, according to results from the CAMERA-MRI II trial published June 8 in JACC: Clinical Electrophysiology.

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