An 80-year-old man presents for a cardiovascular follow-up after a prolonged hospitalization in the setting of an intracerebral hemorrhage. His medical history is relevant for atrial fibrillation, stage 3b chronic kidney disease, heart failure with preserved ejection fraction, hypertension, myocardial infarction 10 years ago, and type 2 diabetes mellitus.
An epigenome-wide association study (EWAS) identified a large number of associations between DNA methylation and carotid, coronary and peripheral atherosclerosis, with >90% of sites traceable to the epigenetic signatures of cardiovascular risk factors, predominantly smoking, according to research published June 3 in JACC.
This episode is part of ACC’s ongoing effort to improve recognition and diagnosis of arrhythmias in clinical practice. In this CardiaCast, faculty explore a modern approach to identifying paroxysmal supraventricular tachycardia (PSVT), with a focus on real-world diagnostic challenges.
An ACC analysis of the preliminary participant list for the Ambulatory Specialty Model (ASM) for Heart Failure found that up to 20% of selected cardiologists may be incorrectly classified under the specialty cardiovascular disease/cardiology.
In this episode, Chief Innovation Officer Dr. Ami Bhatt and Dr. Ankeet Bhatt explore the impact of large language models (LLM) on cardiovascular care today.
The new 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome is the first ever to address the "interrelated condition characterized by the interconnections among metabolic risk factors (including obesity and type 2 diabetes)...
Patients with low plasma renin levels had a more pronounced blood pressure (BP) reduction with spironolactone/dapagliflozin vs. dapagliflozin alone, in addition to seeing a more favorable impact on cardiovascular structure and function, while aldosterone levels exhibited no predictive value in treatment response...
When compared with angiography guidance, quantitative flow ratio (QFR)-guided PCI improved five-year clinical outcomes with benefits primarily achieved in the first two years, according to a follow-up study of the multicenter, sham-controlled FAVOR III trial published June 10 in JACC.
A long-term follow-up of the CENTRAL and DIRECT-PLUS trials published in Circulation suggests that despite long-term weight regain, visceral fat reduction during lifestyle intervention is associated with sustained improvements in metabolic health.
Patients who underwent mitral transcatheter edge-to-edge repair (M-TEER) with an optimal result were more likely to have improved hemodynamics and less likely to experience major adverse events, all-cause mortality, heart failure (HF) hospitalization or reintervention at one year...
When compared with liberal oxygen therapy, conservative oxygen therapy did not improve rates of survival with favorable functional outcomes among unresponsive patients in the intensive care unit (ICU) receiving mechanical ventilation after cardiac arrest, according to results from the investigator-initiated, open-label LOGICAL trial published June 10 in NEJM.
Supplementation with the vitamin K homologue menaquinone-7 (MK-7) significantly attenuated coronary artery calcification (CAC) compared with placebo in adults with symptomatic coronary artery disease (CAD), according to research published June 10 in JAMA Cardiology.
Administration of sodium bicarbonate made no significant difference in the sustained return of spontaneous circulation, compared with placebo, in patients who suffered an in-hospital cardiac arrest, according to research published June 11 in JAMA.
Lipid management remains a cornerstone of secondary prevention in atherosclerotic cardiovascular disease (ASCVD), with increasingly strong evidence supporting its central role across all vascular territories, including coronary, cerebrovascular, and peripheral arterial beds.
In patients with atrial fibrillation (AFib) and left ventricular systolic dysfunction (LVSD), catheter ablation was associated with substantial improvement in LVEF regardless of late gadolinium enhancement (LGE) status, while 12-month LVEF and normalization rates were lower in patients with LGE present, according to results from the CAMERA-MRI II trial published June 8 in JACC: Clinical Electrophysiology.
In this week’s View, Dr. Eagle highlights a study showing race and sex disparities in M-TEER outcomes, with Black patients presenting with more advanced disease, lower success, and higher heart failure readmissions than White patients, and women having lower success rates than men.